![]() LI-COR ® and Odyssey ® are registered trademarks of LI-COR Biosciences Not Intended for Diagnostic or Therapeutic Use.Īlexa Fluor ® is a trademark of Molecular Probes Inc., OR., USA MTMR9 regulates the activity of MTMR7 and MTMR8.įor Research Use Only. ![]() MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR3 and MTMR4 can either interact with each other or self associate. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. MTMR2 Antibody (F-1) is available as both the non-conjugated anti-MTMR2 antibody form, as well as multiple conjugated forms of anti-MTMR2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor ® conjugates. MTMR2 Antibody (F-1) is an IgG 1 κ mouse monoclonal MTMR2 antibody (also designated MTMR2 antibody) suitable for the detection of the MTMR2 protein of mouse, rat and human origin by WB, IP, IF and ELISA. At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MTMR2 Antibody (F-1).Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MTMR2 (F-1): sc-365184.also available conjugated to Alexa Fluor ® 680 or Alexa Fluor ® 790 for WB (NIR), IF and FCM for use with Near-Infrared (NIR) detection systems, such as LI-COR ®Odyssey ®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems.also available conjugated to Alexa Fluor ® 488, Alexa Fluor ® 546, Alexa Fluor ® 594 or Alexa Fluor ® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems.Anti-MTMR2 Antibody (F-1) is available conjugated to agarose for IP HRP for WB, IHC(P) and ELISA and to either phycoerythrin or FITC for IF, IHC(P) and FCM.MTMR2 Antibody (F-1) is recommended for detection of MTMR2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine.specific for an epitope mapping between amino acids 47-77 near the N-terminus of MTMR2 of human origin.MTMR2 Antibody (F-1) is a mouse monoclonal IgG 1 κ MTMR2 antibody, cited in 2 publications, provided at 200 µg/ml.NITROCELLULOSE, PVDF AND NYLON MEMBRANES.AUTORADIOGRAPHY FILM, TAPE AND PLASTIC WRAP.Biologically Active Proteins & Peptides.NUCLEOTIDES, PEPTIDES, PROTEINS & AMINO ACIDS.BIOLOGICALLY ACTIVE & PURIFIED PROTEINS.PROTEIN A, G-PLUS & L AGAROSE IP REAGENTS.ISOTYPE SPECIFIC MOUSE IgG BINDING PROTEINS.POLYCLONAL GOAT/RABBIT ANTI-MOUSE SECONDARY ANTIBODIES.MONOCLONAL MOUSE ANTI-RABBIT/GOAT SECONDARY ANTIBODIES.SBF2 ZNF143 RF00066-030 piR-31534-083 RNU7-28P LOC101928008 LOC124902802Ī mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in individuals with two pathogenic alleles, either homozygotes (two copies of the same mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele).Īutosomal recessive Autosomal recessive form Autosomal recessive predisposition biallelic_autosomalĪbnormality of head or neck Head and neck abnormalityĪbnormal tongue Abnormality of the tongue Glossal abnormality Lingual abnormality Tongue abnormalityĪbnormality of the oral cavity, i.e., the opening or hollow part of the mouth. ZIC2 FEZF1 FOXA2 HOMEZ MAFF ZNF316 FOSL2 TEAD3 ZFP91 MAFK SP1 ZNF580 POLR2A KLF17 JUND NCOR1 ZNF184 CTCF ZNF600 ZIC2 KLF6 KLF17 POLR2A ZIC2 YY1 CEBPA CEBPB MAZ ZNF592 NONOĮPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER KLF6 POLR2A DPF2 ATF2 KLF17 JUND NCOR1 ATF3 CTCF ZNF600ĪDM-DT SBF2 AMPD3 ADM ZBED5 CTR9 RPL21P97 WEE1 ENSG00000254397 CAND1.11 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER
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